Progress and Clinical Translation of 3D Bioprinting Technology in Orthopedics Surgery报告人:
Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University
Professor Jinwu Wang（M.D.）, chief physician of Department of Orthopedics, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, part-time professor and doctoral supervisor of Shanghai Jiao Tong University School of Biomedical Engineering. Now he is the deputy director of Key Laboratory of Intelligent Control and Rehabilitation Technology of Ministry of Civil Affairs, the excellent technical leader in Shanghai, the leader of Key disciplines of Bone and Joint Rehabilitation of Shanghai Municipal Commission of Health and Family Planning, the director of innovation center for rehabilitation AIDS of Shanghai Jiao Tong University, the evaluation expert of CFDA, and the chief scientist of national key research and development program of ministry of science and technology.
He has focused on the clinical research of osteoarthrosurgery, peripheral nerve, 3D printing of digital medicine, etc. He has been supported by 24 grants, including the National Key Research and Development Program, the sub-projects of National High-tech R&D Program of China (863 Program) and National Program on Key Basic Research Project of China (973 Program), the National Science Foundation of China and a number of ministerial and provincial scientific research projects. In addition, he has published over 80 research papers in high-impact journals as the first author or corresponding author, including 20 SCI papers. He was enrolled into “Shanghai Rising-Star Program”, “Shanghai Pujiang Plan” and “Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support”. He has earned the first prize of “National Medical Science and Technology Progress Award” in 2011, “Shanghai Rehabilitation Medical Science and Technology Progress Award” in 2014 and 2019. He has also honored as “The People of the Year Awards 2016” by Scientific Chinese and “Excellent Academic Leader of Clinical Rehabilitation” by Shanghai Association of Rehabilitation Medicine. He and his research group were granted the first registration certificate of 3D printing medical device in China, which is also the first domestic registration certificate of medical device applied by scientific research enterprises under the new registration system.
Progress and Clinical Translation of 3D Bioprinting Technology in Orthopedics Surgery
Biological 3D Printing is a technology based on computer-aided design (CAD), which can locate and assemble biomaterials or living cells by using the method of software delamination and numerical control to manufacture biomedical products such as biological scaffolds, tissues, organs and personalized products. With the development of 3D printing technology, the personalized medical products can not only achieve "adjustable scale and size", but also satisfy the diverse needs such as different anatomical structures, mechanical properties, biological functions, and so on. From the initial incompatibility materials to the latest 4D printing technology, it has gone through five stages of development. And the three most widely used types are inkjet, extrusion and laser.Although biological 3D printing technology has achieved some gratifying results and has shown great advantages and potentials, it is still in the exploratory stage facing many problems to be solved as soon as possible, such as the limitation of printing materials, the insufficiency of biological function, the deficiency of hardware and software, and the difficulties in regulatory approval by CFDA.