挤出式生物3D打印形性协同研究/Pushing the rheological and mechanical boundaries of extrusion-based 3D bioprinting
报告人:欧阳礼亮
所在单位:清华大学
个人简介:
欧阳礼亮,清华大学助理教授、特别研究员、博士生导师。2012和2017年分获清华大学学士和博士学位,先后在宾夕法尼亚大学和帝国理工学院从事研究工作。出版生物3D打印独作英文专著1本(Springer),在Science Advances, Advanced Materials, Materials Today等期刊发表生物制造相关的学术论文二十余篇(SCI他引1500余次),包括3篇ESI高被引研究论文(第一作者)。获得国际生物制造学会(ISBF)青年科学家奖、GE科技创新大赛一等奖等荣誉。目前担任国际期刊International Journal of Bioprinting(IF=6.638)副主编,国际生物制造学会(ISBF)青年学者委员会委员。
报告摘要:
3D bioprinting has long been subjected to trade-offs between physicochemical and biological outcomes. The resulting material properties of the initial bioinks and final printing products usually lie within a moderate range, which limits the application of bioprinting and its products. Recent progress in bioinks and bioprinting techniques has significantly expanded the window of material properties. In this talk, I will define two bioprinting windows to clarify the trade-offs between physical chemistry and biology and introduce our recent work that have pushed the rheological boundaries of bioinks and mechanical boundaries of bioprints, focusing on unusual material properties. I will mainly introduce how we harness innovative forms of bioinks and bioprinting strategies (e.g., guest-host supramolecular bioink, complementary network bioink, in-situ crosslinking bioprinting and void-free bioprinting approaches) to meet the requirements of engineering functional living constructs. I will also consolidate the existing strategies into well-defined categories, highlight the prominent trends, and provide perspectives on additional boundaries.