Dr. Kai Tao is a Professor at the School of Mechanical Engineering, Zhejiang University. Dr. Tao graduated his PhD from China University of Petroleum (East China), under the co-supervision of Prof. Jian R. Lu and Prof. Hai Xu, studying peptides-based soft materials and superstructures. He then joined Prof. Ehud Gazit’s lab at Tel Aviv University of Israel for postdoctoral research, studying biomimetic integration and engineering. After joining in Zhejiang University In 2020, Dr. Tao’s research interests focus on self-assembling manufacturing, biomimetic integration engineering and surface functional structures manufacturing, materials-structures-devices integration and biology-machine interfaces.
Short Peptides Self-Assembling Manufacturing
Ordered supramolecular organizations comprised of metabolic small molecules, such as short peptides, extensively participate in the naturally biological activities. Learning from nature, biomimicry of these naturally supramolecular assemblies will facilitate the fabrication of eco-friendly functional integrations by simple bio-organic building blocks. The flexible and unique properties of the short peptides self-assemblies can be utilized for numerous bio/nano technological applications, such as the construction of soft, smart bio-organic functional devices. In addition, the intrinsic biocompatibility of the assemblies can bridge the gaps between smart devices and the biological world. This may allow monitoring and sensing of a wide variety of metabolic activities, as well as analysis, and possibly interference, of the biological system, by rational design of the self-assembling architectures. With these goals in mind, the short peptides integration systems can provide a promising technological tool for fundamental biology, biomedicine, bionanotechnology and advanced device engineering studies.
This talk will introduce our accumulated progress on biomimetic assembly integration engineering, emphasizing the design, interfacial adsorption & modification, self-assembly and integration of metabolic organizations, especially short peptides self-assemblies. Subsequently, our findings regarding their diverse physicochemical properties, including optical, mechanical, electric, semiconductive and piezoelectric behaviors, will be presented. Simultaneously, our ongoing studies and future plans will also be discussed.